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Pathological study of Korean native pregnant cows and fetuses
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experimentally vaccinated with Brucella abortus RB51 in heifers
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and challenged with Brucella abortus 2308 in pregnancy
You-Chan Bae, Gye-Hyeong Woo, Ha-Young Kim, Moon Her, Dong-Hee
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Cho, Suk-Chan Jung, Jae-Ku Oem, Jae-Won Byun, Yi-Seok Joo, O-Soo Lee,
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Myoung-Heon Lee
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¼ö·ÏÀâÁö Çѱ¹¼öÀÇ°øÁߺ¸°ÇÇÐȸÁö 36(3) : 109-113
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Abstract :
Bovine brucellosis causes abortion and infertility. The authors conducted this study to
determine pathological lesions of Korean native cows and fetuses experimentally
vaccinated with Brucella abortus RB51 and challenged with Brucella abortus 2308. The
gross and histopathological lesions in endometrium and placenta in cows of vaccinated
group were observed. Twenty-five percent of pregnant cattle in vaccinated group
showed endometritis and placentitis, which was three times lower than non-vaccinated
group. The pathological lesions in uterus and placenta in both groups were consistent
with the previous reports. Therefore, the vaccination in heifers using Brucella abortus
RB51 may not have enough efficacy to protect Brucella abortus virulent strain infection.
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