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m/z was also investigated, comparing the single compound?s concentration. From the
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same experiments by MRM, misrecognition and abundance increasing between native
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and stable isotope under single or mixture compounds were found. Due to the same
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monitored fragment ions of the different sulfonamides, cross-talk occurred to induce the
false positive result. Otherwise, it is assumed that cross-talk does not depend on the
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manufacturers? instrument and spectrometer types of LC-MS.
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