총 1147페이지
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Risk assessment and scoring for environmental contaminants
Title
resided in livestock products.
Researcher
Sang-Hee Jeong, Jeong-Woo Kang, Joon-Hyoung, Cho et al
- Abstract -
Environmental contaminants can be accumulated into livestock animals via
breathing spread particles, feeding contaminants or drinking. Concerns on
the safety of livestock products have been increased according to the
increased of environmental contamination. This study was performed to
score the risk priority of many environmental contaminants that can be
resided or contaminated in livestock products based on risk assessment.
All kinds of information on toxicity, accumulation and human or animal
exposure wall compiled via EPA, Toxnet, JECFA, CODEX and etc. To
develop risk assessment procedure fitting to residual environmental
contaminants in livestock products and to rank the risk priority for risk
management, we assessed the risk of 95 environmental contaminants that
are approved for use and have potential impact on human health according
to the procedures of hazard identification, hazard characterization,
exposure assessment and risk characterization based on the all compiled
data. 28 environmental contaminants were selected as candidates that can
be resided in livestock products and induce adverse effects on human
health and classified into 5 categories according to their characteristic. All
scientific information for risk assessment of the selected contaminants
were compiled and classified into direct and indirect hazardous factors,
exposure factors and reference factors. The data on toxicity (T),
exposure risk (ER, MOE), maximum residue limit (MRL) and residue
violation rate for recent 5 years (RV) were allocated into hazardous
factors and data on accumulation ratio (AR) and residual risk (RR,
TMDI/ADI) were categorized into exposure factors. The limit of
information on residue violation rate (LI) was referred to reference
factors. All factors were ranked into 0 to 5 and risk of each chemicalwas
calculated according to the equation drawn by optimal weighing on
toxicity, MRL and exposure risk. The equation for risk scoring was:
[residue
violation
rate×5.8
or
estimated
risk:
(3×MRL
+2×RR+2×AR)+(2×ER+3×T)/2]×{1+0.06667×(LI-1)}. Among the 28
environmental contaminants assessed, dioxin was the highest risky
residual contaminants scored as 40.33 and followed by Acrylamide, AFM1,
AFB1 and Hexachlorobenzene in order. The model developed by the
present study for the determination of risk priority of environmental
contaminants resided in livestock products may provide the basis for the
decision
of
risk
management.
The
highly
ranked
environmental
contaminants in risk priority are assumed to have potent public health
impact by ingestion of animal originated food and should be controlled
intensively for the prevention of environmental contaminants in food in
risk management.
Risk assessment, environmental contaminants, livestock
Keyword
products, Food safety
- 1093 -
Title
resided in livestock products.
Researcher
Sang-Hee Jeong, Jeong-Woo Kang, Joon-Hyoung, Cho et al
- Abstract -
Environmental contaminants can be accumulated into livestock animals via
breathing spread particles, feeding contaminants or drinking. Concerns on
the safety of livestock products have been increased according to the
increased of environmental contamination. This study was performed to
score the risk priority of many environmental contaminants that can be
resided or contaminated in livestock products based on risk assessment.
All kinds of information on toxicity, accumulation and human or animal
exposure wall compiled via EPA, Toxnet, JECFA, CODEX and etc. To
develop risk assessment procedure fitting to residual environmental
contaminants in livestock products and to rank the risk priority for risk
management, we assessed the risk of 95 environmental contaminants that
are approved for use and have potential impact on human health according
to the procedures of hazard identification, hazard characterization,
exposure assessment and risk characterization based on the all compiled
data. 28 environmental contaminants were selected as candidates that can
be resided in livestock products and induce adverse effects on human
health and classified into 5 categories according to their characteristic. All
scientific information for risk assessment of the selected contaminants
were compiled and classified into direct and indirect hazardous factors,
exposure factors and reference factors. The data on toxicity (T),
exposure risk (ER, MOE), maximum residue limit (MRL) and residue
violation rate for recent 5 years (RV) were allocated into hazardous
factors and data on accumulation ratio (AR) and residual risk (RR,
TMDI/ADI) were categorized into exposure factors. The limit of
information on residue violation rate (LI) was referred to reference
factors. All factors were ranked into 0 to 5 and risk of each chemicalwas
calculated according to the equation drawn by optimal weighing on
toxicity, MRL and exposure risk. The equation for risk scoring was:
[residue
violation
rate×5.8
or
estimated
risk:
(3×MRL
+2×RR+2×AR)+(2×ER+3×T)/2]×{1+0.06667×(LI-1)}. Among the 28
environmental contaminants assessed, dioxin was the highest risky
residual contaminants scored as 40.33 and followed by Acrylamide, AFM1,
AFB1 and Hexachlorobenzene in order. The model developed by the
present study for the determination of risk priority of environmental
contaminants resided in livestock products may provide the basis for the
decision
of
risk
management.
The
highly
ranked
environmental
contaminants in risk priority are assumed to have potent public health
impact by ingestion of animal originated food and should be controlled
intensively for the prevention of environmental contaminants in food in
risk management.
Risk assessment, environmental contaminants, livestock
Keyword
products, Food safety
- 1093 -
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